SS-31 30mg is a research-material keyword associated with SS-31, also known as elamipretide or MTP-131. SS-31 is a synthetic tetrapeptide that has been extensively investigated in mitochondrial and biochemical research.
For researchers evaluating SS-31 materials, chemical identity and analytical documentation are important. PubChem identifies elamipretide with the molecular formula C32H49N9O5, molecular weight 639.8 g/mol, exact mass 639.38566570 Da, and monoisotopic mass 639.38566570 Da. PubChem lists its peptide representation as RXKF, corresponding to D-Arg–2,6-dimethyl-L-Tyr–L-Lys–L-Phe-NH₂.
SS-31 research has focused heavily on mitochondrial biology, membrane interactions, cardiolipin binding, bioenergetics, and related cellular processes. Scientific studies have examined the peptide in experimental systems, while research and clinical development should be distinguished from the specifications of a particular research-material product.
SS-31 30mg at a Glance
| Property | SS-31 / Elamipretide |
|---|---|
| Product keyword | SS-31 30mg |
| Common name | SS-31 |
| Chemical name | Elamipretide |
| Alternative name | MTP-131 |
| Peptide class | Synthetic tetrapeptide |
| Sequence representation | RXKF |
| Molecular formula | C32H49N9O5 |
| Molecular weight | 639.8 g/mol |
| Exact mass | 639.38566570 Da |
| Monoisotopic mass | 639.38566570 Da |
| Research focus | Mitochondrial and biochemical research |
| Common analytical methods | HPLC, LC-MS, mass spectrometry |
| Product amount discussed | 30mg |
The 30mg quantity refers to the amount of material represented by the product keyword and should not be confused with molecular weight or analytical purity. Actual product specifications should always be verified against the batch-specific documentation supplied with the material.
What Is SS-31?
SS-31 is a synthetic peptide commonly identified as elamipretide. It belongs to the Szeto-Schiller family of mitochondria-targeted peptides.
Chemically, PubChem describes elamipretide as an oligopeptide and gives the condensed peptide representation H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH₂. Its molecular formula is C32H49N9O5.
Unlike a conventional linear peptide composed entirely of standard L-amino acids, SS-31 contains a D-arginine residue and a dimethylated tyrosine component. This structural configuration is relevant when researchers are evaluating molecular identity and interpreting analytical results.
SS-31 has attracted scientific attention because of its interaction with mitochondrial membranes and the phospholipid cardiolipin.
SS-31 and Mitochondrial Research
Mitochondria are cellular organelles involved in energy metabolism, signaling, and maintenance of cellular homeostasis.
Research into SS-31 has investigated how a mitochondria-targeted peptide interacts with mitochondrial membranes and associated molecular systems.
A PubMed-indexed study reported that SS-31 interacts with cardiolipin-rich mitochondrial membranes and investigated how the peptide affects membrane surface electrostatics and lipid organization.
Other research has examined SS-31 interactions with mitochondrial proteins involved in oxidative phosphorylation and related metabolic pathways. One study used chemical cross-linking and mass spectrometry to characterize SS-31-associated mitochondrial protein interactions.
These findings make SS-31 relevant to several areas of laboratory research, including:
- Mitochondrial biology
- Peptide chemistry
- Membrane biophysics
- Cellular metabolism
- Mass spectrometry
- Protein interaction studies
- Bioenergetics
- Molecular biology
Importantly, experimental findings should be interpreted according to the model, methodology, and endpoints used in each individual study.
SS-31 Molecular Weight
The molecular weight of SS-31, identified as elamipretide in PubChem, is:
639.8 g/mol
PubChem calculates this value from the molecular formula C32H49N9O5.
Molecular weight is useful for general chemical identification and documentation. However, researchers conducting analytical characterization may also need the exact mass and monoisotopic mass.
SS-31 Molecular Data
Molecular formula: C32H49N9O5
Molecular weight: 639.8 g/mol
Exact mass: 639.38566570 Da
Monoisotopic mass: 639.38566570 Da
These values describe the parent elamipretide molecule. Salt or counterion forms can have different molecular formulas and masses. For example, PubChem separately identifies TFA-associated and hydrochloride forms.
SS-31 Exact Mass
The reported exact mass of parent elamipretide is:
639.38566570 Da
PubChem reports the same numerical value for its monoisotopic mass.
Exact mass can be especially useful in high-resolution mass spectrometry because researchers can compare calculated theoretical values with experimentally observed molecular-ion signals.
However, an analytical sample may contain counterions, adducts, solvent, degradation products, or other molecular species. Consequently, the theoretical parent-peptide mass should be treated as an identity reference rather than automatically assumed to be the observed mass of every physical preparation.
SS-31 Peptide Sequence and Structure
SS-31 is a tetrapeptide.
Its PubChem sequence representation is:
RXKF
The expanded structural representation is:
D-Arg–2,6-dimethyl-L-Tyr–L-Lys–L-Phe-NH₂.
This structural description is important because simply calling SS-31 a four-amino-acid peptide does not fully describe its chemical architecture.
The presence of modified residues and a D-amino-acid component should be considered when interpreting:
- Molecular formula
- Exact mass
- Mass spectra
- Synthetic identity
- Chromatographic retention
- Reference standards
- Certificate-of-analysis information
For SEO purposes, terms such as SS-31 sequence, SS-31 peptide structure, and elamipretide molecular weight naturally complement the primary keyword SS-31 30mg.
SS-31 30mg Research Material
The term SS-31 30mg generally indicates a specified quantity of SS-31 research material.
For a laboratory-focused product page, quantity should be presented separately from chemical identity.
For example:
Product amount: 30mg
Molecular weight: 639.8 g/mol
Exact mass: 639.38566570 Da
Formula: C32H49N9O5
The amount of material and the molecular weight answer different questions.
A 30mg product specification describes the quantity supplied, whereas molecular weight describes the mass of an individual mole of the parent compound.
Researchers should also distinguish product quantity from peptide purity. A vial containing a stated amount of material does not by itself establish that the entire quantity consists exclusively of the target peptide.
SS-31 Purity Testing
Purity is an important consideration when evaluating a research peptide.
For SS-31, analytical documentation may include chromatographic and mass-spectrometric information.
HPLC Testing
High-performance liquid chromatography can separate chemical components according to their interactions with the chromatographic system.
An SS-31 HPLC report may contain information such as:
- Retention time
- Principal peak
- Relative peak area
- Chromatographic conditions
- Reported purity
- Testing date
- Batch or lot identification
A reported HPLC percentage should be understood as the result of the particular analytical method rather than as an absolute statement that no other molecular species exist.
Mass Spectrometry
Mass spectrometry can provide molecular-mass information supporting peptide identity.
An analytical report may include:
- Calculated mass
- Observed mass
- Charge state
- Mass spectrum
- Molecular-ion assignment
- Instrument method
HPLC and MS therefore provide complementary information.
SS-31 COA: What Should Researchers Look For?
A Certificate of Analysis (COA) can provide batch-specific information about a research material.
For SS-31 30mg, researchers may look for:
1. Product Identification
The COA should clearly identify the material being tested.
2. Batch or Lot Number
A lot number helps connect the analytical report to a specific material batch.
3. Purity Result
The document may report an HPLC or other analytical purity value.
4. Mass-Spectrometry Information
MS results can support molecular identity.
5. Testing Date
The testing date provides context for the analytical report.
6. Analytical Method
The method used to obtain the result can help researchers understand what was actually tested.
7. Laboratory Information
Where available, testing-laboratory information can provide additional traceability.
For a research-oriented product page, displaying or linking the relevant batch documentation can be more useful than relying exclusively on a headline purity percentage.
Why HPLC and LC-MS Matter for SS-31
Analytical characterization becomes particularly important for synthetic peptides because chemical identity is more complex than a product name.
HPLC can help researchers examine chromatographic composition.
LC-MS can combine chromatographic separation with molecular-mass information.
Together, these techniques can provide a more complete analytical picture.
For SS-31, the theoretical molecular information provides an analytical reference:
Formula: C32H49N9O5
Molecular weight: 639.8 g/mol
Exact mass: 639.38566570 Da
Researchers can then compare the theoretical identity with experimentally generated analytical data.
SS-31 and Mass Spectrometry Research
Mass spectrometry has been used directly in scientific research involving SS-31.
For example, researchers have used chemical cross-linking combined with mass spectrometry to investigate mitochondrial protein interactions involving SS-31. The study identified interacting proteins associated with mitochondrial metabolic pathways and cardiolipin-binding systems.
This illustrates why SS-31 is relevant not only as a peptide chemistry subject but also as an analytical research material.
Mass-spectrometry applications can include investigations of:
- Peptide identity
- Molecular mass
- Protein-peptide interactions
- Mitochondrial protein systems
- Membrane-associated interactions
- Experimental peptide characterization
SS-31 and Cardiolipin Research
One of the most frequently discussed scientific characteristics of SS-31 is its interaction with cardiolipin.
Cardiolipin is an important phospholipid associated with the inner mitochondrial membrane.
Research has investigated how SS-31 interacts with cardiolipin-containing membranes and how these interactions influence membrane properties. A 2020 biophysical study reported that SS-31 partitions into membrane interfacial regions and modulates surface electrostatics.
This research provides a scientific basis for studying SS-31 in membrane biophysics and mitochondrial research.
It does not, by itself, establish a particular outcome for every experimental model or commercial research material.
SS-31 Research Applications
SS-31 has been investigated in a variety of experimental contexts.
Mitochondrial Biology
Researchers investigate mitochondrial structure, membrane behavior, bioenergetics, and signaling.
Membrane Biophysics
SS-31’s interaction with cardiolipin-containing membranes makes it relevant to membrane-interaction experiments.
Cellular Metabolism
Research has examined mitochondrial metabolic pathways and cellular energy processes.
Protein Interaction Research
Mass-spectrometry-based approaches have been used to investigate mitochondrial protein interactions.
Peptide Chemistry
Researchers can examine SS-31’s unusual structural characteristics, including its modified tyrosine and D-arginine component.
SS-31 30mg vs. Elamipretide
The names SS-31 and elamipretide refer to the same underlying peptide compound in the chemical literature.
Other names appearing in scientific and chemical databases include MTP-131 and Bendavia. PubChem lists these synonyms alongside elamipretide.
For SEO, this creates a useful keyword cluster:
- SS-31 30mg
- SS-31 peptide
- SS-31 research peptide
- elamipretide
- elamipretide research
- MTP-131
- SS-31 molecular weight
- SS-31 exact mass
Using these terms naturally can help a page address multiple related search queries without keyword stuffing.
SS-31 Research: Scientific Context
The scientific literature on elamipretide is broader than a simple peptide identity page.
A recent review describes elamipretide as a mitochondria-targeted tetrapeptide and summarizes research into its structure, cardiolipin interaction, mitochondrial biology, and experimental applications.
Other PubMed-indexed studies have investigated SS-31 in experimental mitochondrial systems, including studies of mitochondrial ADP sensitivity and bioenergetic processes.
This literature should be separated from product-specific claims. Scientific research on a compound does not automatically establish the quality, purity, or characteristics of an individual commercial batch.
How to Evaluate an SS-31 Research Peptide
A laboratory evaluating an SS-31 research material can organize its review around several categories.
Identity
Confirm the stated chemical identity, synonym, sequence, and formula.
Molecular Data
Compare the listed molecular weight and exact mass with authoritative chemical references.
Purity
Review the reported analytical purity and methodology.
HPLC
Look for chromatographic evidence associated with the specific batch.
Mass Spectrometry
Review MS data supporting molecular identity.
COA
Check that documentation corresponds to the actual lot or batch.
Traceability
Keep product and analytical documentation with laboratory records.
This approach provides a more useful quality framework than relying on a product title alone.