Melanotan II Molecular Weight: Formula, Exact Mass & Research Guide
Melanotan II Molecular Weight
The molecular weight of Melanotan II is 1,024.2 g/mol (Da) for the parent compound. PubChem lists Melanotan II with the molecular formula C₅₀H₆₉N₁₅O₉, an exact mass of approximately 1,023.5403 Da, and CAS Registry Number 121062-08-6.
Understanding the molecular weight of Melanotan II is useful for researchers working with peptide identification, analytical chemistry, mass spectrometry, molecular characterization, and research documentation.
It is also important to distinguish Melanotan II itself from its acetate salt or other formulated forms. PubChem lists Melanotan II acetate with a molecular weight of approximately 1,084.2 g/mol, reflecting the presence of acetic acid in the salt form

For this reason, researchers should always identify the exact chemical form specified by a certificate of analysis, analytical report, or reference database before comparing molecular-weight data.
Research-use notice: This page provides chemical and analytical information for research and educational purposes. It does not provide instructions for human administration, dosing, injection, tanning, treatment, or self-use.
What Is the Molecular Weight of Melanotan II?
The reported molecular weight of the parent Melanotan II molecule is:
1,024.2 g/mol
PubChem identifies the compound as Melanotan II, with the molecular formula:
C₅₀H₆₉N₁₅O₉
Its reported exact/monoisotopic mass is:
1,023.54026884 Da
PubChem’s current record identifies CAS 121062-08-6 and PubChem CID 92432.
These values are useful in analytical research because molecular weight and exact mass provide different types of chemical information.
Key Melanotan II molecular data
| Property | Melanotan II |
|---|---|
| Molecular weight | 1,024.2 g/mol |
| Molecular formula | C₅₀H₆₉N₁₅O₉ |
| Exact mass | 1,023.54026884 Da |
| Monoisotopic mass | 1,023.54026884 Da |
| CAS number | 121062-08-6 |
| PubChem CID | 92432 |
| Research abbreviation | MT-II / MT2 |
Source: PubChem.
Molecular Weight vs. Exact Mass
One of the most important concepts for peptide analytical research is the distinction between molecular weight and exact mass.
Although these terms are sometimes used interchangeably in general product descriptions, analytical scientists use them differently.
Molecular Weight
Molecular weight is generally expressed in g/mol and represents the weighted average based on naturally occurring isotopic abundances.
For Melanotan II, PubChem reports:
1,024.2 g/mol
Exact Mass
Exact mass is calculated using the masses of the specific isotopes represented in a molecular formula.
For Melanotan II, PubChem reports:
1,023.54026884 Da
This distinction becomes particularly important when interpreting mass-spectrometry results.
A product page that simply states “Melanotan II molecular weight” may therefore benefit from presenting both values rather than treating them as identical measurements.
Melanotan II Molecular Formula
The molecular formula for Melanotan II is:
C₅₀H₆₉N₁₅O₉
This indicates that the parent compound contains:
- 50 carbon atoms
- 69 hydrogen atoms
- 15 nitrogen atoms
- 9 oxygen atoms
PubChem identifies Melanotan II as a synthetic cyclic peptide and provides the molecular structure, sequence information, identifiers, and computed chemical properties.
The molecular formula is particularly useful when researchers need to:
- Verify chemical databases
- Compare analytical records
- Interpret mass spectra
- Check reference standards
- Evaluate molecular-weight calculations
- Compare supplier documentation
- Build laboratory databases
- Develop analytical methods
A molecular formula should always be associated with the correct chemical form because salts and other forms can have different reported molecular weights.
Melanotan II Exact Mass
The exact mass of Melanotan II is approximately 1,023.5403 Da.
PubChem reports:
1,023.54026884 Da
as both the exact mass and monoisotopic mass.
Exact-mass information can be especially valuable when researchers use high-resolution mass spectrometry.
High-resolution analytical instruments can distinguish compounds that may have similar nominal masses but different elemental compositions.
For peptide characterization, the theoretical exact mass can therefore serve as a reference point when evaluating experimental mass-spectrometry data.
However, an observed mass signal should not be interpreted in isolation. Experimental results can be influenced by:
- Ionization state
- Instrument calibration
- Adduct formation
- Sample preparation
- Salt forms
- Matrix effects
- Instrument resolution
- Peptide modifications
- Analytical conditions
Consequently, molecular-weight information is best used as one part of a broader analytical characterization process.
Melanotan II Molecular Weight and Mass Spectrometry
Mass spectrometry is one of the most useful analytical techniques for investigating peptide molecular identity.
When a peptide such as Melanotan II is analyzed using mass spectrometry, the instrument does not simply display a single molecular-weight number. Depending on the ionization technique and instrument configuration, researchers may observe different charge states and corresponding mass-to-charge ratios.
For a peptide with a molecular weight around 1,024 Da, multiple ionization states can be relevant.
Researchers may therefore use:
- Molecular formula
- Theoretical mass
- Exact mass
- Observed mass-to-charge ratio
- Charge-state distribution
- Isotopic pattern
- Chromatographic retention
- Reference material
to evaluate whether an analytical result is consistent with the expected compound.
This is one reason why a Melanotan II COA containing mass-spectrometric information can provide useful additional information beyond a standalone purity percentage.
Melanotan II HPLC and Molecular Weight
High-performance liquid chromatography, or HPLC, provides information that is complementary to mass spectrometry.
HPLC can separate components within a sample and generate a chromatographic profile.
Researchers may examine:
- Main chromatographic peak
- Retention time
- Secondary peaks
- Reported chromatographic purity
- Analytical method
- Reference standard
- Sample identification
Mass spectrometry can then provide molecular-mass information associated with detected components.
This creates a useful analytical distinction:
HPLC → chromatographic separation and purity information
Mass spectrometry → molecular-mass and identity-supporting information
Neither measurement should automatically be treated as a complete characterization of every property of a peptide.
Melanotan II Molecular Weight and COA Verification
A Certificate of Analysis (COA) can provide valuable batch-specific information when evaluating a research peptide.
For a Melanotan II research material, researchers can compare the COA against established chemical information.
A useful verification process can include:
1. Confirm the compound name
Check that the product designation corresponds to Melanotan II.
2. Check the batch number
The COA should correspond to the specific batch or lot being evaluated.
3. Review molecular identity information
Where available, review mass-spectrometric or other identity-testing results.
4. Review purity data
Determine the analytical method used to generate the reported purity value.
5. Check the chemical form
Determine whether the documentation refers to the parent compound, acetate salt, or another form.
6. Compare theoretical and experimental values
Where mass spectrometry is reported, researchers can compare the experimental analytical profile with the expected molecular characteristics.
7. Maintain documentation
Keep the COA and analytical records associated with the laboratory material and batch.
Melanotan II vs. Melanotan II Acetate Molecular Weight
This is an important technical distinction for anyone researching Melanotan II molecular weight.
PubChem lists the parent compound as:
Melanotan II — 1,024.2 g/mol
with molecular formula:
C₅₀H₆₉N₁₅O₉.
PubChem separately lists Melanotan II acetate with:
Molecular weight: 1,084.2 g/mol
and molecular formula:
C₅₂H₇₃N₁₅O₁₁.
Another PubChem record for Melanotan II acetate salt identifies the same 1,024.2 g/mol parent-compound value in a particular representation, illustrating why researchers should inspect the exact chemical record and formulation rather than assuming that every “acetate” notation represents the same reporting convention.
For SEO content and laboratory documentation, the safest approach is to specify the chemical form explicitly.
Why Chemical Form Matters
A molecular-weight value cannot be interpreted correctly without knowing what chemical entity is being measured.
For example, a laboratory document might describe:
- Melanotan II
- Melanotan II acetate
- A peptide salt
- A formulated research preparation
- A reference standard
These descriptions may correspond to different molecular compositions or reporting conventions.
Therefore, researchers should avoid assuming that a number printed on one supplier’s page automatically applies to another material.
The exact chemical form should be confirmed through:
- COA
- Product specification
- Analytical report
- Reference database
- Mass spectrometry
- Supplier documentation
Melanotan II Molecular Structure
Melanotan II is described in PubChem as a synthetic cyclic heptapeptide. PubChem provides a condensed sequence representation and structural identifiers for the compound.
Structural information can be relevant to research involving:
- Peptide chemistry
- Molecular modeling
- Receptor-ligand research
- Analytical characterization
- Structure-function studies
- Computational chemistry
- Peptide identification
A molecular structure image can also make technical content easier to understand for researchers who are comparing related peptide compounds.
For an SEO page targeting “Melanotan II molecular weight,” including the molecular formula and structure provides useful supporting information rather than repeating the same keyword.
Melanotan II Chemical Identifiers
Several identifiers can help researchers distinguish Melanotan II from similarly named compounds.
Common name
Melanotan II
Alternative notation
Melanotan-II
Abbreviations
MT-II and MT2
CAS Registry Number
121062-08-6
PubChem CID
92432
Molecular formula
C₅₀H₆₉N₁₅O₉
Molecular weight
1,024.2 g/mol
These identifiers are reported by PubChem and can be useful when searching scientific databases or cross-checking supplier documentation.
Melanotan II Research Applications
Melanotan II has been studied in the context of melanocortin biology and peptide research.
For a research-oriented website, it is preferable to describe these areas scientifically rather than making claims about human outcomes.
Potential research categories include:
Peptide chemistry
Researchers can investigate synthetic peptide structure, stability, analytical properties, and chemical characterization.
Receptor research
Melanotan II has been studied in relation to melanocortin receptor biology.
Analytical chemistry
Its molecular characteristics make it suitable as a subject for chromatographic and mass-spectrometric investigation.
Structure-function studies
Researchers can examine relationships between peptide structure and receptor-related activity.
Comparative peptide analysis
Melanotan II can be compared analytically with related peptide compounds under controlled research conditions.
The specific research application should always be determined by the laboratory’s approved protocol and applicable requirements.
Melanotan II Molecular Weight for Peptide Research
Molecular-weight information is useful at several stages of a research workflow.
Procurement
Researchers can compare supplier documentation with established chemical references.
Sample identification
The expected molecular mass can provide a reference point for analytical characterization.
Mass spectrometry
Theoretical mass can be compared with experimentally observed data.
Documentation
Molecular information can be incorporated into laboratory records and analytical reports.
Database management
Chemical identifiers can help laboratories maintain organized compound databases.
Research reproducibility
Clear reporting of molecular identity and chemical form makes it easier to reproduce analytical work.
Important Limitations of Molecular Weight
Molecular weight alone does not establish:
- Purity
- Identity with absolute certainty
- Sterility
- Stability
- Biological activity
- Safety
- Manufacturing quality
- Suitability for a particular experiment
For example, a sample can have an expected molecular-mass signal while still containing additional components.
That is why a complete analytical evaluation may use multiple techniques.
A researcher’s assessment can include:
Identity + HPLC + MS + COA + batch traceability + appropriate laboratory documentation
rather than relying on molecular weight alone.
Melanotan II Analytical Quality Testing
A comprehensive analytical strategy can include several complementary measurements.
HPLC
Provides chromatographic separation and purity information.
LC-MS
Combines chromatographic separation with mass-spectrometric detection.
High-resolution MS
Can provide more precise mass information useful for molecular characterization.
Reference comparison
Reference materials can provide useful comparison points where appropriately validated.
COA review
Batch-specific documentation connects analytical results to the supplied material.
The exact analytical testing required depends on the research application and laboratory quality system.
Research-Use Wording for Melanotan II
For a research-oriented product page, appropriate language should remain consistent throughout the page.
Recommended wording
“Melanotan II is presented on this page as a research material for qualified laboratory and analytical investigation.”
“For research and educational purposes only.”
“Not intended for human or veterinary use.”
“This page does not provide instructions for administration, dosing, injection, tanning, diagnosis, or treatment.”
Avoid wording that suggests that a research material is an approved pharmaceutical or that laboratory information establishes suitability for human use.
The FDA currently lists Melanotan II among substances for which compounded drugs may present significant safety risks, citing potential immunogenicity concerns associated with aggregation or peptide-related impurities.
Frequently Asked Questions
What is the molecular weight of Melanotan II?
The molecular weight of Melanotan II is 1,024.2 g/mol, according to the current PubChem record.
What is the molecular formula of Melanotan II?
The molecular formula is C₅₀H₆₉N₁₅O₉.
What is the exact mass of Melanotan II?
PubChem reports an exact and monoisotopic mass of approximately 1,023.54026884 Da.
What is the CAS number for Melanotan II?
The CAS Registry Number listed by PubChem is 121062-08-6.
Is Melanotan II molecular weight the same as Melanotan II acetate?
Not necessarily. PubChem lists the parent Melanotan II at 1,024.2 g/mol, while Melanotan II acetate is listed at approximately 1,084.2 g/mol.
Why is molecular weight important in mass spectrometry?
Theoretical molecular mass provides a reference for interpreting experimental mass-to-charge measurements and can support molecular characterization.
Does molecular weight prove peptide purity?
No. Molecular weight alone does not establish purity. Researchers generally need additional analytical information such as chromatographic and identity data.
What does HPLC tell researchers?
HPLC can provide chromatographic separation and purity information under a specified analytical method. It does not by itself establish every aspect of molecular identity.
What does a Melanotan II COA provide?
A batch-specific COA may provide information such as product identity, batch number, analytical methods, purity results, and other quality-control information.
Is Melanotan II approved for human use?
The FDA currently identifies Melanotan II among substances associated with potential safety risks in compounded drugs and notes concerns involving immunogenicity, aggregation, and peptide-related impurities.
Why should researchers identify the chemical form?
Parent Melanotan II and salt forms can have different molecular compositions and reported molecular weights. Correct chemical-form identification helps prevent errors when comparing analytical data.